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Seek immediate medical attention for severe or persistent abdominal pain (especially if radiating to the back), persistent vomiting, inability to keep fluids down, or right upper quadrant pain with fever or yellowing of the skin, which could indicate serious conditions such as pancreatitis or gallbladder disease

Persistent mucosal injury and inadequate epithelial regeneration contribute to disease progression and complications, often necessitating surgical intervention

These findings implicate a role for the metabolic reprogramming of local immune cells in the antitumor therapy

AT A GLANCE Weight loss is more than just calorie counting