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Simulated ESR spectra of DEPMPO-trapped radicals (80% GS, 20% C) (lower traces), based on the following parameters: DEPMPO-SG(80 %): g iso = 2.00440, a H1 = 15.4 G, a H2 = 0.9 G, a p = 45.9 G, a NO = 14.1 G

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Conclusions Skeletal muscle wasting is a frequent and clinically significant complication in patients with T2D and obesity, which is exacerbated by chronic inflammation, insulin resistance and metabolic dysregulation

Maximum injectable dose 2.4 mg weekly