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In turn, this phenomenon can triggers a catalytic mechanism for the oxidation of the cellular thiol pool [117,118,119] and of oxidative stress when the homeostatic compensation is overwhelmed by an excessive depletion of the reduced thiol pool, as is the case for cells, such as neurons, that depend on neighboring glial cells for their supply of essential thiol precursors

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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Kurutas E.B

"Twice daily N-acetylcysteine 600 mg for exacerbations of COPD (PANTHEON)." Lancet Respir Med