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Description

In an experimental model using adult mice exposed to a mixture of OPFRs (triphenyl phosphate, TPP, tricresyl phosphate, TCP, and tris(13-dichloro-2propyl)phosphate, TDCPP, 1 mg/kg of each), on a low-fat diet (LFD) or HFD, males exhibited elevated activity and oxygen consumption, while in females these parameters were decreased, irrespective of diet [271]

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Functional FAD depletion without structural mutations has also been reported in other mitochondrial disorders

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