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I mean, as a layoutside person, this seems like a big deal

If rotator cuff pain is so intense that you cant do physical therapy or exercise, your doctor may recommend a steroid injection

2014 Oct;18(19):2942-8

Improvements in Endothelial Dysfunction Among the most significant outcomes was the improvement in endothelial function, demonstrated by an increase in flow-mediated dilation (FMD) and a reduction in asymmetric dimethylarginine (ADMA), a known endogenous inhibitor of nitric oxide synthase and marker of endothelial dysfunction