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This significant discrepancy between physiological requirements and therapeutic doses highlights the need for a deeper understanding of B12 absorption dynamics, rather than focusing solely on intake quantity

Lentiviral vectors (LV), adeno-associated virus (AAV), and lipid nanoparticles (LNP) are among the most studied delivery systems for intra-articular applications

The active shedding phase often lasts several weeks to a few months

Additionally, South Asian adults who are older and have a lower BMI are more likely to discontinue the medication due to the heightened impact of side effects, particularly weight loss