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Additionally, there is no data addressing outcomes in patients who do not need weight loss but are using GLP-1 agonists solely to improve metabolic health

The cardiovascular outcomes trial SUSTAIN-6, published in the New England Journal of Medicine, demonstrated cardiovascular safety in a population where many participants were receiving antiplatelet therapy

Patients may be more stringently screened, particularly for thyroid nodules/cancer in patients receiving GLP-1 receptor agonists

Nature 535 , 182186 (2016)