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Formally known as Melanotan II, this synthetic cyclic heptapeptide is one of the most widely studied non-selective melanocortin agonists in preclinical science, and its multi-receptor engagement profile makes it a uniquely powerful tool for researchers investigating the broader melanocortin signalling system, rather than any single receptor subtype in isolation

Cell Death Dis 2013;4:e626 [DOI] [PMC free article] [PubMed] [Google Scholar] 43.Ye D, Wang Y, Li H, Jia W, Man K, Lo CM, Wang Y, Lam KS, Xu A.Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1alpha-mediated antioxidant capacity in mice

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