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[15] In August 2024, the SURMOUNT-1 three-year study (176-week treatment period) found that tirzepatide reduced the risk of developing type 2 diabetes by 94% in adults with pre-diabetes and obesity or overweight

The implications extend beyond diabetes, with broad applications in oncology, neurodegenerative, and inflammatory diseases, potentially accelerating the development of new treatments

This means that GLP-1 therapies may gradually expand from specialist treatment settings to broader chronic disease management markets

It promotes angiogenesis (the growth of new blood vessels needed for healing), accelerates tendon-to-bone and Achilles repair, and reduces inflammation, partly by activating the FAK-paxillin cell-migration pathway and upregulating growth-hormone receptors in tendon cells (Molecules, 2014