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Possible reasons for bowel prep to work slower than expected include: Constipation before taking prep solution: Constipation is when someone experiences difficulty passing bowel movements, and chronic constipation can slow bowel function, impacting when prep solutions work

Fidgeting less, walking less, standing less

In particular, changes in alcohol and nicotine use (both directly affecting sedation and recovery) may be more common than expected but not always captured in routine documentation

Sargeant JA, Brady EM, Zaccardi F et al (2020) Adults with early-onset type 2 diabetes (aged 18-39 years) are severely underrepresented in diabetes clinical research trials