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Commensal bacteria, such as Lactobacillus, synthesize neurotransmitters like gamma-amino butyric acid (GABA), dopamine, noradrenaline, and histamine, which are essential for neurophysiological and neurodevelopmental processes (114)

High uric acid directly inhibits insulin signalling and induces insulin resistance

The use of GSH-AuNCs as probes in conjunction of fluorescence and X-ray computed tomography (CT) imaging platforms has been reported in vitro and in vivo 17,19

As discussed before in this manuscript, BBB breakdown is considered to be the basic pathophysiology of HT, and BBBP is directly correlated with the appearance of subsequent HT, suggesting that the assessment of the BBB permeability should be the most promising predictor of HT (154)