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STEP-HFpEF Trial (NEJM, 2023): 13.3% weight loss plus major improvements in HFpEF symptoms and function

Everybody Needs a Different Dose He explains that because everybody's body is different, it's important to work with your own clinician to determine the proper dose

It helps reduce oxidative stress, fight free radicals, and regulate melanin production the pigment responsible for skin color

Excess adiposity, particularly visceral fat, contributes to dyslipidemia through multiple pathways involving insulin resistance, increased hepatic lipogenesis, and altered lipoprotein metabolism