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Interpretation: Splinting has benefit, but not as much as injection, and is best used in combination with injection Clinical reasoning Splinting - best to include thumb and wrist Reduces thumb abduction and wrist deviation Minimises APL/EPB (1st dorsal compartment) mechanical irritation Best chance of being effective when used during sleep as well as waking hours Activity modification Much easier conceptually than practically

Deconstructing the Core Therapies: The Science of LDN and Peptides To understand the power of the combined protocol, its essential to appreciate how each component works

To visualise similarities between groups of samples in this data set a principal component analysis (PCA) was performed

Geng, H