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In a randomized controlled trial involving patients with cirrhosis and CHE, dietary intervention with protein intake of 1.01.5 g/kg/day led to significant improvement in CHE and was associated with more favorable clinical outcomes compared with a standard diet [118]

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Their clinical trials (NCT04542161) conclusively demonstrated that ME/CFS patients suffer from a significant, localized deficit of glutathione in the cerebral cortex, directly correlating with the severity of their neuroinflammation and cognitive dysfunction

Cerebrolysin's modest but replicated clinical effects represent more actionable scientific knowledge than Dihexa's dramatic but unconfirmed preclinical claims