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Testosterone replacement therapy is a prescription treatment for diagnosed hypogonadism

Multiple randomized controlled trials demonstrate that GLP-1 receptor agonists produce 15-22% body weight reduction over 68 weeks in patients with obesity

10 "Insulin-like growth factor 1 - Wikipedia." Accessed 29 Jul

However, the disadvantage of a peptide drug is its short circulating plasma half-life and unfavorable parenteral drug delivery [12, 13]