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Jones et al., 2016

It is also present in many foods, like watermelons, cucumbers, and pumpkins

Veterinary Hematology, Clinical Chemistry, and Cytology

166,167,172 As the endogenous peptide suffers from rapid metabolic degradation, they introduced multiple modifications, such as epimerization at position 8 and two lactam bridges, and produced highly constrained GLP-1 analogs