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Although the higher potency of other biguanides, such as phenformin, led to their prioritization in clinical trials (42), the development of lactic acidosis led to early discontinuation of the trials and the interest in Metformin was reignited (43, 44)

Egan AG, Blind E, Dunder K, et al

The next phase of growth here wont just be about accessitll be about building the clinical and regulatory infrastructure to support it responsibly