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Though we did not observe differences in total astrocyte or myelin protein expression, we noted an increase in Iba1, reflective of increased microglia

J Biol Chem 282:3045265, PMID: 17724027 Ji L, Shen K, Jiang P, Morahan G, Wang Z (2011) Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells

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In fact, no ordered water molecule is found in the crystal structure at that location