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The most commonly reported adverse effects of semaglutide are gastrointestinal in nature, affecting a substantial proportion of patients

Among current preventive and therapeutic strategies, probiotic interventions have gained considerable recognition as a promising option (445)

Conversely, norepinephrine and -adrenergic agonists inhibit (84) and -adrenergic agonists stimulate (52, 182) GLP-1 secretion suggesting that sympathetic neural innervation of the gut is also important in the regulation of GLP-1 secretion

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