(179) used transcriptome analysis to reveal mitochondrial shrinkage, lipid peroxidation, ROS accumulation, and increased PUFA levels in Cyp4v3 (homolog of human CYP4V2) knockout mouse RPE cells
Overall 32.2% of subjects had LH at only one site, and 65.8% of patients had LH at several site levels, primarily the abdomen (52.4%), followed by thighs (23.2%), arms (19.9%), and other unusual areas (4.5%), including the thigh area located immediately distal to the crural region, the areas immediately above the knee, and the proximal arm region (34.2%)
Neurotoxicology 23:223251 Soares MVL, Alves Filho EG, Silva LMA, Novotny EH, Canuto KM, Wurlitzer NJ, Narain N, de Brito ES (2017) Tracking thermal degradation on passion fruit juice through nuclear magnetic resonance and chemometrics
It initiates the inflammatory response by binding to its receptors, TNF- type 1 receptor expressed on all human tissues and type 2 receptor mainly expressed in immune cells (10)