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Additionally, depression raises markers for epithelial barrier dysfunction, such as zonulin, leading to increased intestinal permeability and circulating lipopolysaccharide (LPS) levels

As a precautionary measure, the medication is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Beyond-use dates may vary depending on the specific formulation

Additionally, psychological factors including stress, sleep quality, and eating behaviours influence outcomes