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Longevity pathways: NAD is required for sirtuins, proteins involved in stress resistance, metabolism, and healthy aging

Corticosteroids may reduce Wegovy's weight loss efficacy by increasing appetite, causing fluid retention, and promoting insulin resistance, though Wegovy's appetite-suppressing effects may help mitigate steroid-induced hunger

Beyond Weight Loss: Because the affected pathways are linked to impulse control and addiction, these drugs are showing potential for treating compulsive behaviors like smoking or alcohol use

Will future trials truly reflect the diverse communities that carry the highest burden of obesity, sleep apnea and cardiometabolic disease