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This rebound effect is likely related to physiologic mechanisms triggered by weight reduction that induce compensatory changes in energy balance homeostasis, including increased appetite and reduced energy expenditure [1417]

While it has shown great results for weight loss, it has potential barriers that make the search for an alternative administration method popular

2023 Population data from the CDC shows that in 23 states more than 1 in 3 adults has obesity, with notable differences by race, age, ethnicity, and socioeconomic class

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