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Throughout their lifetime, there is an abundant number of exposures that can cumulatively impact the quality of the egg

Localized to the plasma membrane, FSP1 utilizes NADPH as an electron donor to reduce CoQ10 to its antioxidant form, ubiquinol

Notably, in patients with SBS or after jejuno-ileal bypass surgery, delivery of an increased amount of undigested carbohydrates to the colon can result in excess d-lactate accumulation (185, 186)

10.1038/nrneph.2017.123 160