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10.1007/s00401-019-02010-2 4 AlfaidiM.BarkerR

The same principles apply across the class

The study cannot explain why lean body mass loss was greater with tirzepatide, which mimics the hormones GLP-1 and GIP, compared with semaglutide, which only mimics GLP-1

In response to the heightened oxidative stress associated with malignant transformation, cancer cells activate a comprehensive antioxidant defense pathway that, paradoxically, shields them from ferroptotic cell death (4)