There are risks: muscle loss without resistance training, potential side effects (especially if dosing is rushed), weight regain if the medication is stopped without behavior change, and still some areas where science is catching up (eyes, thyroid, mental health, long-term safety in certain populations)
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Vitamin B12 Depot Panpharma must not be used if you are hypersensitive (allergic) to hydroxocobalamin acetate or any of the other ingredients of the medicine
You simply cannot ramp up to the exercise intensity required to burn fat if you are dehydrated