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Unlike sulfonylureas, which stimulate insulin secretion independently of blood glucose and can lead to hypoglycemia, GLP-1RAs improve glycemic control in a glucose-dependent manner, thereby minimizing the risk of hypoglycemia

3.4 Endoscopic interventions Endoscopic sleeve gastroplasty (ESG) involved creating a two-row plication, effectively reducing the size beginning from the gastroesophageal joint to the prepyloric antrum by forming a narrow sleeve-like structure (63)

Intermediate courses bring a noticeable reduction in appetite suppression and upward glucose drift

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