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This approval is based on its ability to help individuals achieve significant weight loss when used in conjunction with a reduced-calorie diet and increased physical activity

Disproportionality signals for IGE All five GLP-1RAs had statistically significant reporting odds ratios (RORs) for IGE: Semaglutide: ROR 24.8 Dulaglutide: ROR 14.7 Liraglutide: ROR 13.7 Exenatide: ROR 5.4 Tirzepatide: ROR 18.3 This analysis confirms that these drugs are significantly more likely to be reported in conjunction with IGE compared to other medications

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The singer became the face of the treatment after her widely circulated before-and-after photos showed a dramatic change from her once tan skin to a noticeably fairer complexion