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Some symptoms, from more minor to severe, impaired judgment and coordination walking difficulty slurred speech mood change behavior change nausea vomiting low body temperature memory loss double vision involuntary eye movement trouble breathing coma respiratory failure heart rhythm changes liver failure Chronic alcohol poisoning leads to alcohol-related liver disease

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One of the most commonly cited trials (Arjinpathana & Asawanonda, 2012) used 500mg per day over 4 weeks and reported a significant reduction in melanin index versus placebo

This extended contact time helps the active compounds work more effectively on stubborn body tan