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(1996), who demonstrated resistance to APAP-induced hepatotoxicity in CYP2E1 knockout mice, indicating that CYP2E1 is the key enzyme responsible for the metabolic conversion of APAP into the active hepatotoxic NAPQI

Association of body iron stores with low molecular weight iron and oxidant damage of human atherosclerotic plaques

A majority of Nrf2 activators can also regulate mitochondrial dynamics via the inhibition of mitochondrial fission and promotion of mitochondrial fusion in kidney diseases

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