Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society 39(5):676679 Olloquequi J, Cornejo-Crdova E, Verdaguer E, Soriano FX, Binvignat O, Auladell C, Camins A (2018) Excitotoxicity in the pathogenesis of neurological and psychiatric disorders: therapeutic implications
Appropriate in drug reconstitution with a 28-day expiration period after first puncture
Our data confirm that CM-EVs maintain their structural integrity, characterized by a preserved cup-shaped bilayer morphology, a consistent nano-size distribution (30150 nm), and only a minimal reduction in characteristic exosomal markers (CD63, CD81, TSG101) post-digestion
Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)