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Description

554 ApoE activates the PI3K/AKT pathway and then inhibits autophagy degradation of ferritin, thereby avoiding iron-dependent lipid peroxidation

As previously mentioned, PRMT7-mediated methylation enhances GLUD1 protein stability and promotes gastric cancer cell proliferation

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These trials represent the closest any T4-related compound has come to therapeutic development, though the program has not resulted in FDA approval as of February 2026