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A similar pattern was observed in SEC-bearing mice receiving GSE or AA as monotherapy, with no significant difference compared to DOX-treated animals from day 11 until the end of the experiment

Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

First, it helps to provide adequate oxygen supply to cells, ensuring cellular energy production and overall vitality

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