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Similar warnings regarding acute pancreatitis, including rare necrotising and fatal cases, are already reflected in regulatory product information from the European Medicines Agency (EMA), the US (FDA), and the Australian (TGA) This does not negate the benefits of these therapies when appropriately prescribed, but it reinforces the importance of: careful patient selection ongoing clinical monitoring and avoiding unsupervised or online use without proper medical assessment Particularly relevant as GLP-1based therapies are increasingly sought by midlife women for weight management, often outside structured medical programmes
Some studies have evaluated L-arginine in doses between 2.8 and 6 mg/day for up to 6 weeks, and have reported beneficial effects, - but these studies have not evaluated the subjective improvements using a validated questionnaire, and thus the results remain circumspect
This expansion has also brought increased scrutiny
And in that sense, encourage anti-inflammation pathways as well as cellular longevity pathways
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