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52 Neurodegenerative disease Animal studies suggest that GLP-1 analogues exert a range of beneficial effects on cognitive function in models of Alzheimers disease

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In diet-induced obese mice (16 weeks HFD), subcutaneous 5-Amino-1MQ treatment for 11 days (20 mg/kg/injection, three injections daily) produced significantly reduced body weights, white adipose tissue masses, and adipocyte cell sizes compared to vehicle controls

High alcohol preference rodents exert elevated EWcp/UCN1 levels 21,22,23 , whereas low alcohol preference is associated with low EWcp/CART mRNA and peptide levels 17