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These effects often diminish over time as patients adjust to therapy

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These include: Vegetarians and vegans, as vitamin B12 is mainly found in animal products Older adults, as they absorb vitamin B12 less well with age People with gastrointestinal disorders, like celiac disease or Crohns disease, which can block vitamin B12 absorption Those taking certain medications, such as proton pump inhibitors or metformin, which can also block vitamin B12 absorption Its best to talk to a healthcare professional about whether you need vitamin B12 supplements

Publication Bias Positive findings are generally more likely to be published than negative studies