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Metsera is running a parallel Phase IIb study of MET-097i, which has already been fully enrolled and is expected to release early data in mid-2025

J Thyroid Res (2013) 2013:424163

Wang N, Zhang L, Lu Y, Zhang M, Zhang Z, Wang K, et al

Chronic inflammation, oxidative stress, and ferroptosis are thought to induce chondrocytes to excessively generate catabolic factors, resulting in the degradation of chondrocytes and ECM, hence accelerating the degeneration of articular cartilage in OA [41-46]