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Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider

(12) The potential actions of ipamorelin on bone cells and tissues in these controlled murine research models include increased deposition of mineral content and expanded cortical bone cross-sectional area, but seemingly not through altering the inherent mineral concentration of the bone matrix itself

doi: 10.1016/j.carbon.2014.09.044