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The key pathological hallmarks of AD include amyloid-beta (A) plaque accumulation, neurofibrillary tangles of hyperphosphorylated tau, chronic neuroinflammation, oxidative stress, and mitochondrial dysfunction (Lv et al., 2020)

Phospholipid hydroperoxide glutathione peroxidase (GPX4) Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity)

doi: 10.1038/s41398-019-0654-8 167 PretzschCMFreybergJVoinescuBLythgoeDHorderJMendezMAet al

The discussion analyses and compares the fusion mechanism with other class III viral fusion proteins (Figs