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Description

Those who needed dose reduction were younger than those who remained at full dose (mean age difference, 6.8 years

Paracetamol works primarily through inhibition of prostaglandin synthesis in the central nervous system , though its exact mechanism of action is not fully understood

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Some studies suggest that VEGF promotes neuroprotection by signaling through the neuropilin receptor expressed in DA neurons, and indirectly by activating the proliferation of astroglia and by promoting angiogenesis [32,131,132]