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The effective blood-brain barrier mechanism impeding the transport of monoamines has been attributed to both the presence of tight junctions cementing adjacent endothelial cells of the cerebral capillary walls, along with high concentrations of dopa decarboxylase and monoamine oxidase (MAO) in the cerebral capillary endothelium (Bertler et al, 1966

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This guide ranks ten of the most prominent US peptide companies, from specialized research suppliers to the industrial Contract Development and Manufacturing Organizations (CDMOs) that serve pharmaceutical clients

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