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As these patterns emerge, we can now identify two distinct consumer segments - the first is current users dealing with side effects, and the second is past users focused on weight maintenance. For current users, side effects represent a major concern, Sibley explained, noting that up to 50% report some kind of side effect, mostly gastrointestinal: nausea, vomiting, diarrhea, constipation, etc. GLP-1 drug user demographics The key GLP-1 drug users sit between the 25 and 44 age mark