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It should be looked at like chemotherapy and surgery for cancer, Pratt said

Up to now the best way to measure insulin in blood consisted of giving both a test dose and a range of standard doses of insulin to mice and then seeing how quickly they developed convulsions from a rise in their blood sugar (hyperglycemia)

The complete amino acid sequence', Canadian Journal Biochemistry , 49, 867-72

Without that guidance, it is easy to get off track or lose hope if results are slower than expected