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The peptide increases expression in 59% of affected genes while suppressing 41%, essentially resetting pathological gene patterns back to healthier states

While behavioral modifications and dietary restrictions constitute cornerstone interventions, pharmacological agents play a pivotal role, particularly in cases where lifestyle interventions alone prove insufficient [4]

ElSayedNAAleppoGArodaVRBannuruRRBrownFMBruemmerDet al

Lidocaine can also increase the expression of ACSL4 by directly knocking down miR-424-5p to promote lipid peroxidation in ovarian cancer cells and increase their sensitivity to the ferroptosis activators erastin and RSL3 (88)