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A subset of patients experienced a recurrence of symptoms when restarting the same drug or a different DPP-4 inhibitor

Holding weekly medications for one week could worsen glycemic control in some patients, interrupt weight-management therapy, require bridging plans, increase patient confusion, and lead to procedure delays or cancellations

Hydrogen peroxide assay The H 2 O 2 content in cells or liver tissue was measured by a Hydrogen Peroxide Assay Kit (Beyotime, S0038), and the OD value was detected by absorption spectroscopy (562 nm)