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Involvement of the gut microbiota in IR Influencing factors of Gut microbiome composition The microbes living in the human gut are key contributors to host metabolism and immune function through mediating the interaction between the host and environment, or releasing metabolites and cytokines

[1] [2] However, the situation becomes more complex when fatty liver disease progresses to non-alcoholic steatohepatitis (NASH) , characterised by inflammation and liver cell damage, or advances to fibrosis or cirrhosis

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