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Without a glucagon arm, semaglutide does not directly offset that decline

In addition to the glucoregulatory and central appetite-suppressive effects of GLP-1 receptor agonists, this drug class also exhibit gastrointestinal effects by inhibiting gastric emptying as well as having intestinotrophic and gut immunomodulatory properties 18,19,20,21,22

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330, 339 Satuli-Autere, S