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While coagulation is necessary to prevent bleeding, excessive clotting can lead to conditions such as thrombosis, which can result in heart attacks or strokes

The beneficial effects of caffeine and coffee extracts on liver fibrosis have been demonstrated in several standard rodent models of experimental liver fibrosis induced by dimethylnitrosamine (DMN), carbon tetrachloride (CCl 4 ), and thioacetamide (TAA), and protective effects of filtered coffee were found in most of the published studies (Furtado et al., 2012

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