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0.6mg dose: 6.2% average weight loss 2.4mg dose: 12.5% average weight loss 3.6mg dose: 13.2% average weight loss 4.8mg dose: 14.9% average weight loss (planned treatment analysis) 4.8mg dose: 18.7% average weight loss (actual treatment received analysis) Placebo: 2.8% average weight loss The distinction between planned treatment and actual treatment received analyses matters

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On-demand access to recorded presentations will be available to registered participants following the conclusion of the meeting, from June 10August 10

Its effect is mediated through D2 receptors (D2Rs) in the brain, pancreas and pituitary gland thus regulating appetite, circadian rhythms, insulin and prolactin release (Lopez Vicchi et al., 2016)