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Taking things slower can lower this risk
In November 2022, the HSE had to write to every GP to advise them against prescribing the medication to patients without diabetes.
For example, in a double-blind, placebo-controlled study of 49 subjects, those receiving 550 mg of Berbevis twice daily for two months showed significant improvements in blood lipids, blood sugar control, total fat mass (-6%), and abdominal (visceral) fat mass (-11%)
In some cases, physicians prescribe semaglutide off-label for weight management in non-diabetic people with obesity, though this use depends on local regulations and medical judgment
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